APICE project develops its actions within 5 study areas of 4 MED space Countries belonging to the regions of Veneto and Liguria (Italy), Provence-Alpes-Côte d'Azur (France), Cataluňa (Spain) and Central Macedonia (Greece) and involve some of the most important port-cities of Mediterranean space.

The project areas show common features related to the port-areas systems (in terms of harbour-industrial district organization) and present the same problems of air-pollution affecting seriously not only the density populated urban centres but also the whole natural ecosystems and the cultural heritage (the project territories count several Sites of Community Importance & Special Protection Areas in their surroundings, as well as UNESCO sites).